Endocrine Abstracts

Hyponatraemia is a common biochemical abnormality associated with significant mortality. However, adequate investigation and accurate diagnosis are frequently lacking. We have evaluated the assessment and management of severe hyponatraemia in a large teaching hospital. Inpatients with a plasma sodium (pNa) <125mmol/L were identified prospectively by laboratory database, over a 6 month period. Notes were examined and data extracted. Data was also retrospectively reviewed by ...

Growth hormone deficiency (GHD) is associated with adverse changes in lipid profile. There are no longitudinal studies of lipid abnormalities in childhood-onset GHD into adulthood. In order to more accurately define the metabolic consequences of GHD in childhood progressing through to adulthood we have examined lipid levels in a group of untreated severely GHD patients with a mutation in the GHRH receptor gene from a rural community in Northeast Brazil.1...